Description du livre
The book presents the latest findings
on C-type lectin receptors, focusing on individual receptors and their
signaling. In recent years there have been great advances in the understanding
of the function of these receptors as a newly emerging family of pattern-recognition
receptors (PRRs) for pathogen-associated molecular patterns (PAMPs) and
damage-associated molecular patterns (DAMPs). Comprising four parts:
ITAM-coupled Activating Receptors; HemITAM-bearing Receptors; ITIM-bearing
Receptors; and Other Receptors and Related Topics, this comprehensive review
covers a broad range of C-type lectin receptors. The updated information on
C-type lectin receptors and their ligands provided will appeal to a wide
readership, from basic immunologists to physicians and surgeons. In addition,
sections on novel drug development make this a valuable resource for
pharmaceutical scientists.