George E. Barreto earned his PhD in Neuroscience (2009) from Universidad Complutense Madrid (Spain) studying the effects of neurosteroids on reactive glia with aging. His post-doctoral training at Stanford University School of Medicine (2009-2011) focused on addressing the role of astrocytes activation following stroke and enhance astrocytic functions targeting neuronal protection. Dr. Barreto is currently a Lecturer in Cell Biology/Immunology at University of Limerick, Ireland. His research interests focus on deciphering the neuropathological mechanisms induced by accumulation of lipids in glial cells, identifying different mechanisms by which hormones can affect brain lipid metabolism and how lipids accumulation can induce neuroinflammation in absence of brain-synthesized estradiol. He is also interested in immune and neuroendocrine aspects of glial cells as a pathological mechanism in many neurological diseases. He has published over 200 peer-reviewed manuscripts, 12 book chapters,and participated as speaker in several international congresses/meetings.Amirhossein Sahebkar received her Pharm.D and PhD (in Pharmaceutical Biotechnology) degrees from the Mashhad University of Medical Sciences (MUMS; Mashhad, Iran), and is currently serving as a faculty member at the Department of Medical Biotechnology (School of Medicine), and Biotechnology Research Center of MUMS, with an adjunct title at the Metabolic Research Centre, University of Western Australia (Perth, Australia). His research focuses on the investigation of novel lipid-modifying agents, including natural products, for the management of severe dyslipidemias (including familial hypercholesterolemia) and atherosclerotic cardiovascular disease. He has published over 800 publications on peer-reviewed international scientific journals, wrote several books and book chapters and presented numerous communications in international and national congresses. He is among ESI-listed top 1% of the world highly cited researchers in two fields: Pharmacology & Toxicology and Clinical Medicine. He is also a member of several national and international scientific committees and organizations.