Biotherapeutics

From small to large molecules and cells

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Éditeur :

Springer

Paru le : 2025-03-05

This book reviews biotherapeutics from a medicinal chemistry perspective. It covers proteins, nucleic acids, low molecular weight hormones, small peptides, extracellular vesicles, gene therapy, cell-based products, and tissue-engineered products. Expert contributors provide insights into the mechani...
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Éditeur

Collection
n.c

Parution
2025-03-05

Pages
355 pages

EAN papier
9783031810244

?Victoria Calzada, MSc, PhD, is Assistant Professor at Faculty of Sciences, Universidad de la República, Montevideo-Uruguay. In her current position, she is working with aptamers as in vivo molecular imaging probes and as biotherapeutics. She is the principal investigator of the national Aptamer group which includes students, national researchers and international collaborators. Dr. Calzada is a young researcher, with several peer-review publications in international journals as well as participated as peer- review in grants and papers. Besides, she has a sustained list of funding for her research program. Thus, since 2016 is distinguished with the Level 1 of the National Research System and she was recently awarded the national L’OREAL-UNESCO award for Women in Science. In addition, the Iberoamerican Network of Aptamers (REDIBA) is coordinated by Dr. Calzada since 2018. Hugo Cerecetto received the Pharmacist degree from Universidad de la República and the Doctor of Philosophy in Medicinal Chemistry from Universidad de Navarra (Pamplona, Spain). He joined the Centro de Investigaciones Nucleares at Facultad de Ciencias-Universidad de la República (Montevideo, Uruguay) as Área de Radiofarmacia responsible in 2013. Prior to coming to Facultad de Ciencias, he served as Professor of Organic Chemistry at the Facultad de Química-Universidad de la República (Montevideo, Uruguay). He has published extensively, almost 260 papers, in the area of medicinal chemistry and specialized R+D+i of new drugs. In 2010, he was awarded the Elsevier-SCOPUS Prize for his publications. He has served on peer review panels and scientific advisory boards at Uruguayan and Ibero-American agencies. Dr. Cerecetto has had an active interest in graduate education for many years. Juan Pablo Tosar, PhD, is Assistant Professor and head of the Analytical Biochemistry Laboratory at Facultad de Ciencias (Universidad de la República, Uruguay). He is also senior researcher at the Pasteur Institute of Montevideo, Uruguay. His research is focused on the design of new analytical techniques for the study of nucleic acids, from electrochemical biosensors to next generation sequencing methods, with an emphasis on extracellular vesicles and extracellular RNA. His group has discovered extracellular ribosomes and extracellular nicked tRNAs, among other relevant scientific contributions. He is currently focused on understanding the mechanisms of RNA-mediated intercellular communication and the recognition of extracellular RNAs by innate immune sensors. He is also interested in exploring new ways to use cell-free RNA molecules as both diagnostic and therapeutic agents.

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EAN PDF
9783031810251
Prix
189,89 €
Nombre pages copiables
3
Nombre pages imprimables
35
Taille du fichier
13148 Ko
EAN EPUB
9783031810251
Prix
189,89 €
Nombre pages copiables
3
Nombre pages imprimables
35
Taille du fichier
30085 Ko

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