Description du livre
The “Novel Therapeutic Targeting in Cancer: An Interdisciplinary Approach” is the twenty sixth volume of the “Interdisciplinary Cancer Research” series, publishes comprehensive volume on novel therapeutic targeting in cancer. The volume starts with a chapter on telomere, DNA damage response, and nanomedicine, as a triad for cancer treatment innovation, followed by two general chapters on precision oncology and interdisciplinary pathways for cancer treatment. Advanced targeting systems for tissue-specific drug delivery and new-generation drug delivery systems as anticancer strategies are the subjects of the following chapters. After discussion on targeting inflammatory proteins for inhibition of cell proliferation in tumor microenviroment, small RNAs, microRNAs, as well as implementing CRISPR/Cas9 and microbiota genomics are explained. Targeting glycan, lectin-based targeted drug delivery systems, proteolysis targeting chimeras, dihydrofolate reductase inhibitors, PARP, ATR, RUVBL1/2 complex, and metal-coordination complexes in cancer treatment are explained in other chapters. Finally, computational advancements and in vitro evaluation in pre-clinical anticancer drug discovery and development are discussed in the last chapter. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for those who wish to have an update on cancer therapeutic targeting.