Özge?Sezin Somuncu is the Organoid Center Director and Senior Scientist in the Department of Radiation Oncology at Dana-Farber Cancer Institute. Her research focuses on cancer biology, with special expertise in patient-derived organoids, DNA damage and repair mechanisms (notably replication stress, USP1 and PARG pathways), and precision oncology. She earned her PhD from Yeditepe University and has held academic positions including Assistant Professor at Bahçesehir University. Her recent work has concentrated on identifying functional biomarkers for drug sensitivity in ovarian cancer models. She has authored numerous peer-reviewed publications, contributed to patent applications, and currently leads collaborative translational projects aimed at improving therapeutic strategies. She currently leads and supports organoid-based translational research, oversees collaborative studies between lab researchers and clinicians and helps integrate organoids into preclinical drug development pipelines.