Description du livre
A broad overview of the interaction of DNA with surfactants and polymers
Due to the potential benefits of biotechnology, interest in the interaction between DNA and surfactants and polymers has become increasingly significant. Now, DNA Interactions with Polymers and Surfactants provides an extensive, up-to-date overview of the subject, giving readers a basis for understanding the factors leading to complexation between DNA and different cosolutes, including metal ions, polyelectrolytes, spermine, spermidine, surfactants and lipids, and proteins.
Topical coverage includes:
Polyelectrolytes, physico-chemical aspects and biological significance
Solution behavior of nucleic acids
Single DNA molecules: compaction and decompaction
Interaction of DNA with surfactants and cationic polymers
Interactions of histones with DNA
DNA-DNA interactions
The hydration of DNA-amphiphile complexes
DNA-surfactant/lipid complexes at liquid interfaces
DNA and DNA-surfactant complexes at solid surfaces
The role of correlation forces for DNA-cosolute interactions
Simulations of polyions
Cross-linked DNA gels and gel particles
DNA as an amphiphilic polymer
Lipid-DNA interactions
Covering both theoretical and practical aspects of the subject, DNA Interactions with Polymers and Surfactants is an ideal resource for chemists and biochemists working in gene and DNA delivery research in industry and academia, as well as for cell biologists, chemical engineers, molecular biologists, and development biologists in the pharmaceutical industry.