Téléchargez le livre : DNA Topoisomerases and Cancer

DNA Topoisomerases and Cancer

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Paru le : 2011-09-21

DNA topoisomerases represent an essential family of DNA processing enzymes and a large number of topoisomerase inhibitors are used clinically for the treatment of various human cancers. Novels drugs are in clinical development both against type I and type II topoisomerases. The book will include bas...
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Description du livre


DNA topoisomerases represent an essential family of DNA processing enzymes and a large number of topoisomerase inhibitors are used clinically for the treatment of various human cancers. Novels drugs are in clinical development both against type I and type II topoisomerases. The book will include basic biochemical and structural reviews for the cancer-relevant topoisomerases. It will describe how topoisomerase dysfunctions can damage the genome and increase the risk of cancers, and the involvement of topoisomerases in programmed cell death. The book will also present the various topoisomerase inhibitors in clinical use and development and their molecular and cellular mechanisms of action.

À propos

Auteur
Yves Pommier
Éditeur
Humana
Collection
Cancer Drug Discovery and Development
Parution
2011-09-21
Pages
443 pages
EAN papier
9781461403227

Auteur(s) du livre


Defaut-Illustration Yves Pommier

Caractéristiques détaillées - droits

EAN EPUB
9781461403234
Prix
210,99 €
Nombre pages copiables
4
Nombre pages imprimables
44
Taille du fichier
2796 Ko
Ce livre est accessible aux handicaps informations d'accessibilité

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