Télécharger le livre :  Pharmacotherapy of Pulmonary Hypertension
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This volume focuses on current evidence-based pharmacological treatments of various forms of pulmonary hypertension and provides a comprehensive review of the latest developments in this area. The first part of the book covers the definition, classification,...

Editeur : Springer
Parution : 2013-10-04
Collection : Handbook of Experimental Pharmacology
PDF, ePub

357,64
Télécharger le livre :  Circadian Clocks
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This book provides the reader with a contemporary and comprehensive overview about the molecular, cellular and system-wide principles of circadian clock regulation. Emphasis is placed on the importance of circadian clocks for the timing of therapeutic interventions.

Editeur : Springer
Parution : 2013-04-18
Collection : Handbook of Experimental Pharmacology
ePub

410,39
Télécharger le livre :  Sphingolipids: Basic Science and Drug Development
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Sphingolipids are lipid components of the plasma membrane in eukaryotic cells. They have an important function in signaling mechanisms in the cell. This book on sphingolipids provides insights into the basics of sphingolipid biology and drug development, with a...

Editeur : Springer
Parution : 2013-04-11
Collection : Handbook of Experimental Pharmacology
ePub

210,99
Télécharger le livre :  Sphingolipids in Disease
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Sphingolipids are lipid components of the plasma membrane of eukaryotic cells with an important function in signaling mechanisms in the cell. This  book provides insight into the physiological and pathophysiological role of sphingolipids and in particular its derivative...

Editeur : Springer
Parution : 2013-04-06
Collection : Handbook of Experimental Pharmacology
ePub

220,49
Télécharger le livre :  Current Antipsychotics
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Six decades after the serendipitous discovery of chlorpromazine as an antipsychotic and four decades after the launch of clozapine, the first atypical or second generation antipsychotic, psychopharmacology has arrived at an important crossroad. It is clear that...

Editeur : Springer
Parution : 2012-11-05
Collection : Handbook of Experimental Pharmacology
ePub

304,89
Télécharger le livre :  Antibiotic Resistance
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This book describes antibiotic resistance amongst pathogenic bacteria. It starts with an overview of the erosion of the efficacy of antibiotics by resistance and the decrease in the rate of replacement of redundant compounds. The origins of antibiotic resistance are...

Editeur : Springer
Parution : 2012-10-22
Collection : Handbook of Experimental Pharmacology
ePub

410,39
Télécharger le livre :  Sex and Gender Differences in Pharmacology
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This is the very first book to deal with sex and gender differences in drug therapy - an increasingly recognized medical need. It starts with an overview on S/G in clinical syndromes and a documentation of the medical and socioeconomic damage caused by gender specific...

Editeur : Springer
Parution : 2012-10-02
Collection : Handbook of Experimental Pharmacology
ePub

304,89
Télécharger le livre :  Novel Antischizophrenia Treatments
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This volume tries to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of...

Editeur : Springer
Parution : 2012-10-01
Collection : Handbook of Experimental Pharmacology
ePub

410,39
Télécharger le livre :  Appetite Control
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The volume ‘Appetite Control’ provides a comprehensive description of the mechanisms controlling food intake, and thereby energy balance, in the mammalian organism.  During the last decade, research in this area has produced a remarkable wealth of information and has...

Editeur : Springer
Parution : 2012-01-18
Collection : Handbook of Experimental Pharmacology
ePub

304,89
Télécharger le livre :  Muscarinic Receptors
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Muscarinic acetylcholine receptors have played a key role in the advancement of knowledge of pharmacology and neurotransmission since the inception of studies in these fields, and the effects of naturally occurring drugs acting on muscarinic receptors were known and...

Editeur : Springer
Parution : 2012-01-06
Collection : Handbook of Experimental Pharmacology
ePub

304,89
Télécharger le livre :  Pediatric Clinical Pharmacology
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The objective of this volume is to give an overview of the present state of the art of pediatric clinical pharmacology including developmental physiology, pediatric-specific pathology, special tools and methods for development of drugs for children (assessment of...

Editeur : Springer
Parution : 2011-09-01
Collection : Handbook of Experimental Pharmacology
ePub

463,14
Télécharger le livre :  Histone Deacetylases: the Biology and Clinical Implication
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The book highlights work from many different labs that taught us abnormal HDACs potentially contribute to the development or progression of many human diseases including immune dysfunctions, heart disease, cancer, memory impairment, aging, and metabolic disorders.

Editeur : Springer
Parution : 2011-08-31
Collection : Handbook of Experimental Pharmacology
ePub

304,89
Télécharger le livre :  Phosphodiesterases as Drug Targets
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Cyclic nucleotide phosphodiesterases (PDEs) are promising targets for pharmacological intervention. Multiple PDE genes, isoform diversity, selective expression and compartmentation of the isoforms, and an array of conformations of PDE proteins are properties that...

Editeur : Springer
Parution : 2011-06-21
Collection : Handbook of Experimental Pharmacology
ePub

304,89
Télécharger le livre :  Diabetes - Perspectives in Drug Therapy
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The chapters of this book report cutting-edge research on molecular events in adiposity and type 2 diabetes, thus opening the way for innovative drug-based therapeutic strategies. It addresses all those who wish to keep in touch with recent developments in the field.

Editeur : Springer
Parution : 2011-04-11
Collection : Handbook of Experimental Pharmacology
ePub

410,39
Télécharger le livre :  Drug Transporters
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It is increasingly recognized that various transporter proteins are expressed throughout the body and determine absorption, tissue distribution, biliary and renal elimination of endogenous compounds and drugs and drug effects. This book will give an overview on the...

Editeur : Springer
Parution : 2010-11-19
Collection : Handbook of Experimental Pharmacology
ePub

304,89
Télécharger le livre :  Methylxanthines
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In the present volume of the Handbook of Experimental Pharmacology well known experts describe the actions of different xanthines with a focus on caffeine and theophylline. A special chapter is devoted to theobromine, an active component of chocolate, the actions of...

Editeur : Springer
Parution : 2010-09-22
Collection : Handbook of Experimental Pharmacology
ePub

410,39
Télécharger le livre :  Fertility Control
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The world’s population is growing at an unsustainable rate. From a baseline ?gure of one billion in 1800, global population is predicted to exceed nine billion by 2050 and 87. 8% of this growth will be localized in less developed countries. Such uneven population growth...

Editeur : Springer
Parution : 2010-09-14
Collection : Handbook of Experimental Pharmacology
ePub

304,89
Télécharger le livre :  Comparative and Veterinary Pharmacology
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The human–animal bond has evolved and diversi?ed down the ages. Dogs, cats and even horses, have long ful?lled the role of faithful companion and indeed, as exempli?ed by the introduction of seeing and hearing dogs, there may be a critical level of co-dependency between...

Editeur : Springer
Parution : 2010-03-10
Collection : Handbook of Experimental Pharmacology
ePub

304,89
Télécharger le livre :  Drug Delivery
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In the view of most experts pharmacology is on drugs, targets, and actions.In the context the drug as a rule is seen as an active pharmaceutical ingredient and not as a complex mixture of chemical entities of a well defined structure. Today, we are becoming more and...

Editeur : Springer
Parution : 2010-03-10
Collection : Handbook of Experimental Pharmacology
ePub

304,89
Télécharger le livre :  Adverse Drug Reactions
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This book provides the current state of knowledge of basic mechanisms of adverse drug reactions (ADRs). The main focus is on idiosyncratic drug reactions because they are the most difficult to deal with. It starts with a general description of the major targets for ADRs...

Editeur : Springer
Parution : 2009-12-18
Collection : Handbook of Experimental Pharmacology
ePub

294,34
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