Tous les ebooks de la collection "Methods & Principles in Medicinal Chemistry" - Wiley-VCH

78 Livre(s)


Ajouter à ma liste d'envies Fragment-based Approaches in Drug Discovery Daniel A. Erlanson , Wolfgang Jahnke This first systematic summary of the impact of fragment-based approaches on the drug development process provides essential information that was previously unavailable. Adopting a practice-oriented approach, this represents a book by professionals for professionals,... Editeur : Wiley-VCH Parution : 2006-12-13 Collection : Methods & Principles in Medicinal Chemistry PDF 248,93 €
Ajouter à ma liste d'envies High-Throughput Screening in Drug Discovery Jörg Hüser Backed by leading authorities, this is a professional guide to successful compound screening in pharmaceutical research and chemical biology, including the chemoinformatic tools needed for correct data evaluation. Chapter authors from leading pharmaceutical companies as... Editeur : Wiley-VCH Parution : 2006-12-13 Collection : Methods & Principles in Medicinal Chemistry PDF 222,55 €
Ajouter à ma liste d'envies Pharmacophores and Pharmacophore Searches Rémy D. Hoffmann , Thierry Langer This handbook is the first to address the practical aspects of this novel method. It provides a complete overview of the field and progresses from general considerations to real life scenarios in drug discovery research. Starting with an introductory historical... Editeur : Wiley-VCH Parution : 2006-12-13 Collection : Methods & Principles in Medicinal Chemistry PDF 174,02 €
Ajouter à ma liste d'envies Pharmacokinetics and Metabolism in Drug Design Dennis A. Smith , Don K. Walker , Han Van De Waterbeemd In this new edition of a bestseller, all the contents have been updated and new material has been added, especially in the areas of toxicity testing and high throughput analysis. The authors, all of them employed at Pfizer in the discovery and development of new active... Editeur : Wiley-VCH Parution : 2006-08-21 Collection : Methods & Principles in Medicinal Chemistry PDF 122,33 €
Ajouter à ma liste d'envies Ligand Design for G Protein-coupled Receptors Didier Rognan , Didier Rognan G protein-coupled receptors (GPCRs) are one of the most important target classes in pharmacology and are the target of many blockbuster drugs. Yet only with the recent elucidation of the rhodopsin structure have these receptors become amenable to a rational drug design.... Editeur : Wiley-VCH Parution : 2006-08-21 Collection : Methods & Principles in Medicinal Chemistry PDF 180,35 €
Ajouter à ma liste d'envies Proteomics in Drug Research Collectif From skillful handling of the wide range of technologies to successful applications in drug discovery -- this handbook has all the information professional proteomics users need. Edited by experts working at one of the hot spots in European proteomic research, the... Editeur : Wiley-VCH Parution : 2006-08-21 Collection : Methods & Principles in Medicinal Chemistry PDF 225,72 €
Ajouter à ma liste d'envies Voltage-Gated Ion Channels as Drug Targets Murali Gopalakrishnan , David Rampe , David J. Triggle , Wei Zheng Edited by the most prominent person in the field and top researchers at US pharmaceutical companies, this is a unique resource for drug developers and physiologists seeking a molecular-level understanding of ion channel pharmacology. After an introduction to the topic,... Editeur : Wiley-VCH Parution : 2006-08-21 Collection : Methods & Principles in Medicinal Chemistry PDF 242,60 €
Ajouter à ma liste d'envies Combinatorial Chemistry Willi Bannwarth , Berthold Hinzen The new edition of this practice-oriented handbook features thoroughly updated contents, including recent developments in parallel synthesis. A new chapter on screening complements the overview of combinatorial strategy and synthetic methods. "Experimental details and... Editeur : Wiley-VCH Parution : 2006-05-12 Collection : Methods & Principles in Medicinal Chemistry PDF 312,23 €
Ajouter à ma liste d'envies G Protein-Coupled Receptors as Drug Targets Roland Seifert , Thomas Wieland With its particular emphasis on the constitutive activity of G-protein-coupled receptors (GPCRs)s, this book comprehensively discusses an important biological process that has not yet been covered in such depth in any other existing books on GPCRs. The international... Editeur : Wiley-VCH Parution : 2006-05-12 Collection : Methods & Principles in Medicinal Chemistry PDF 232,05 €
Ajouter à ma liste d'envies Molecular Interaction Fields Gabriele Cruciani This unique reference source, edited by the world's most respected expert on molecular interaction field software, covers all relevant principles of the GRID force field and its applications in medicinal chemistry. Entire chapters on 3D-QSAR, pharmacophore searches,... Editeur : Wiley-VCH Parution : 2006-05-12 Collection : Methods & Principles in Medicinal Chemistry PDF 174,02 €
Ajouter à ma liste d'envies Microwaves in Organic and Medicinal Chemistry C. Oliver Kappe , Alexander Stadler The authors of this guide are experts on the use of microwaves for drug synthesis as well as having much experience in teaching courses held under the auspices of the American Chemical Society and the IUPAC. In this handy source of information for any practicing... Editeur : Wiley-VCH Parution : 2006-05-12 Collection : Methods & Principles in Medicinal Chemistry PDF 174,02 €
Ajouter à ma liste d'envies BioNMR in Drug Research Oliver Zerbe The vast progress made in the investigation of biomolecules using NMR has only recently been rewarded with the Nobel Prize for Kurt Wuthrich. Edited by a former coworker of Wuthrich, this book presents the theoretical background on NMR of biomolecules, plus the use of... Editeur : Wiley-VCH Parution : 2006-03-06 Collection : Methods & Principles in Medicinal Chemistry PDF 222,55 €
Ajouter à ma liste d'envies Protein-Ligand Interactions Hans-Joachim Böhm , Gisbert Schneider The lock-and-key principle formulated by Emil Fischer as early as the end of the 19th century has still not lost any of its significance for the life sciences.The basic aspects of ligand-protein interaction may be summarized under the term 'molecular recognition' and... Editeur : Wiley-VCH Parution : 2006-03-06 Collection : Methods & Principles in Medicinal Chemistry PDF 134,99 €
Ajouter à ma liste d'envies Drug Bioavailability Per Artursson , Hans Lennernäs , Han Van De Waterbeemd The peroral application (swallowing) of a medicine means that the body must first resorb the active substance before it can begin to take effect.The efficacy of drug uptake depends on the one hand on the chemical characteristics of the active substance, above all on its... Editeur : Wiley-VCH Parution : 2006-03-06 Collection : Methods & Principles in Medicinal Chemistry PDF 134,99 €
Ajouter à ma liste d'envies Chemogenomics in Drug Discovery Hugo Kubinyi , Gerhard Müller Chemogenomics brings together the most powerful concepts in modern chemistry and biology, linking combinatorial chemistry with genomics and proteomics. This first reference devoted to the topic covers all stages of the early drug discovery process, from target... Editeur : Wiley-VCH Parution : 2006-03-06 Collection : Methods & Principles in Medicinal Chemistry PDF 193,01 €
Ajouter à ma liste d'envies Chemoinformatics in Drug Discovery Tudor I. Oprea This handbook provides the first-ever inside view of today's integrated approach to rational drug design. Chemoinformatics experts from large pharmaceutical companies, as well as from chemoinformatics service providers and from academia demonstrate what can be achieved... Editeur : Wiley-VCH Parution : 2006-03-06 Collection : Methods & Principles in Medicinal Chemistry PDF 275,30 €
Ajouter à ma liste d'envies Quantum Medicinal Chemistry Frank Alber , Paolo Carloni Computational methods are transforming the work of chemical and pharmaceutical laboratories. Increasingly faster and more exact simulation algorithms have made quantum chemistry a valuable tool in the search for active substances. Written by a team of leading... Editeur : Wiley-VCH Parution : 2006-03-06 Collection : Methods & Principles in Medicinal Chemistry PDF 153,98 €
Ajouter à ma liste d'envies Molecular Biology in Medicinal Chemistry Theodor Dingermann , Gerd Folkers , Dieter Steinhilber This readily comprehensible book explains the identification of molecular targets via cellular assays, reporter genes or transgenic models, as well as surveying recent advances in the synthesis, separation and analysis of drugs. A special section is devoted to molecular... Editeur : Wiley-VCH Parution : 2006-03-06 Collection : Methods & Principles in Medicinal Chemistry PDF 218,33 €
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