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Sabine Stübler compares different proteasome isoforms and subtypes in terms of their transport and active site-related parameters applying an existing computational model. In a second step, the author extends this model to be able to describe the influence of proteasome...
Editeur :
Springer Spektrum
Parution :
2017-11-30
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The book describes molecular principles and mechanisms by which mitochondrial DNA (mtDNA) can drive the occurrence of diseases and the latest understanding of mtDNA biology.The book explores roles of mtDNA mutation and genetic changes in cancer, with a special focus on...
Editeur :
Springer
Parution :
2017-11-25
Collection :
Advances in Experimental Medicine and Biology
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Five leaders in the field of mammalian preimplantation embryo development provide their own perspectives on key molecular and cellular processes that mediate lineage formation during the first week of life. The first cell-fate decision involves the formation of the...
Editeur :
Springer
Parution :
2017-11-23
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Glutathione (?-glutamyl-cysteinyl-glycine) is a ubiquitously distributed sulfurcontaining antioxidant molecule that plays key roles in the regulation of plant growth, development, and abiotic and biotic stress tolerance. It is one of the most powerful...
Editeur :
Springer
Parution :
2017-11-21
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This book provides a resource of current understandings about various aspects of the biology of spermatogonia in mammals. Considering that covering the entire gamut of all things spermatogonia is a difficult task, specific topics were selected to provide foundational...
Editeur :
Springer
Parution :
2017-11-20
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Introduces all of the essential cell biology and developmental biology background for the study of stem cells This book gives you all the important information you need to become a stem cell scientist. It covers the characterization of cells, genetic techniques for...
Editeur :
Wiley-Blackwell
Parution :
2017-11-17
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This book reviews the functions and roles of DJ-1 in various oxidative stress-related diseases and applications of DJ-1 and its binding compounds to the diseases. The DJ-1 gene was first found to be a novel oncogene in 1997 and later, in 2003, also found to be a...
Editeur :
Springer
Parution :
2017-11-16
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Hemoglobin defects, specifically sickle cell disease & thalassemia, combined, constitute the most common monogenic disorders in the world. In fact, nearly 2% of the world’s population carries a globin gene mutation. The transfer of the corrective globin gene through the...
Editeur :
Springer
Parution :
2017-11-09
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This book discusses the importance of oxidative stress, related biomarkers, and its diagnostic methods including bio-analytical and advanced detection systems. Oxidative stress is associated with diminished capacity of a biological system to overcome the overproduction...
Editeur :
Springer
Parution :
2017-10-24
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The main goal of this book is to form a high-quality platform in which well-known and emerging pioneering basic, translational and clinical scientists can present their latest, exciting findings in the studies of redox signaling in the pulmonary vasculature. Content...
Editeur :
Springer
Parution :
2017-10-18
Collection :
Advances in Experimental Medicine and Biology
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This book elucidates the mechanisms involved in biological membrane functions. It describes the new modalities and characterization for basic in vitro as well as computer models of biological membranes. Biological membranes are analyzed in terms of advances in...
Editeur :
Springer
Parution :
2017-10-04
Collection :
Advances in Anatomy, Embryology and Cell Biology
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This volume focuses on the modulation of biological membranes by specific biophysical properties. The readers are introduced to emerging biophysical approaches that mimick specific states (like membrane lipid asymmetry, membrane curvature, lipid flip-flop, lipid phase...
Editeur :
Springer
Parution :
2017-09-25
Collection :
Springer Series in Biophysics
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This book is the first comprehensive review of drebrin, which plays pivotal roles in various cellular events, via forming unique actin cytoskeletons, including synapse formation and in synaptic function. Particularly the loss of drebrin from dendritic spines is used as...
Editeur :
Springer
Parution :
2017-08-31
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This book focuses on a topical and timely aspect of prokaryotic biology - the biology of prokaryotic multiple chaperonins. Chaperonins are a class of molecular chaperones, the proteins that assist folding of other proteins in the cell. The book begins with an...
Editeur :
Springer
Parution :
2017-08-30
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This book presents the latest advances concerning the regulation of chromosome segregation during cell division by means of centromeres and kinetochores. The authors cover both state-of-the-art techniques and a range of species and model systems, shedding new light on...
Editeur :
Springer
Parution :
2017-08-23
Collection :
Progress in Molecular and Subcellular Biology
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This book provides the first comprehensive coverage of the quickly evolving research field of membrane contact sites (MCS). A total of 16 chapters explain their organization and role and unveil the significance of MCS for various diseases.
MCS, the intracellular...
Editeur :
Springer
Parution :
2017-08-16
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„We wish to suggest a structure for the salt of deoxyribose nucleic acid (D.N.A.). This structure has novel features which are of considerable biological interest“, so lauten die ersten Sätze des berühmten Artikels aus dem Jahr 1953, in dem Francis Crick und James...
Editeur :
Springer Spektrum
Parution :
2017-08-02
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This essential volume presents comprehensive information on cell death and autophagy in liver diseases, including the role and molecular signaling pathways of cell death in alcohol and non-alcoholic fatty liver disease, bile acids, hepatitis C virus and drug-induced...
Editeur :
Springer
Parution :
2017-08-02
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The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes.The scope of coverage is all areas of chemical science including the interfaces with related...
Editeur :
Springer
Parution :
2017-07-08
Collection :
Topics in Current Chemistry Collections
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This atlas presents the results of cases of structural chromosome aberrations based on the currently available methods of analysis for different types of abnormality. It particularly focuses on which spectrum should be chosen when combining the different techniques to...
Editeur :
Springer
Parution :
2017-07-06
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