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Increasing the potency of therapeutic compounds, while limiting side-effects, is a common goal in medicinal chemistry. Ligands that effectively bind metal ions and also include specific features to enhance targeting, reporting, and overall efficacy are driving...
Editeur :
Wiley
Parution :
2014-04-25
PDF, ePub
Offre spéciale
-10%
151,95€
|
Understanding, identifying and influencing the biological systems are the primary objectives of chemical biology. From this perspective, metal complexes have always been of great assistance to chemical biologists, for example, in structural identification and...
Editeur :
Wiley
Parution :
2014-04-14
PDF, ePub
Offre spéciale
-10%
142,95€
|
Squamous cell cancers of the head and neck (SCCHN), also known as head and neck cancers (HNC) encompass malignancies of the oral cavity, larynx, nasopharynx and pharynx, and are diagnosed in over 500,000 patients worldwide each year, accounting for 5% of all...
Editeur :
Springer
Parution :
2014-04-08
Collection :
Current Cancer Research
ePub
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Proteins Biochemistry and Biotechnology 2e is a definitive source of information for all those interested in protein science, and particularly the commercial production and isolation of specific proteins, and their subsequent utilization for applied purposes in industry...
Editeur :
Wiley-Blackwell
Parution :
2014-03-03
PDF, ePub
Offre spéciale
-55%
127,95€
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This work, a sequel to Honeybees and Wax published nearly 30 years ago, starts with a brief introduction and discussion of nesting sites, their spaces and densities, self-organization of nest contents, and interspecific utilization of beeswax. The following chapters...
Editeur :
Springer
Parution :
2014-02-21
ePub
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Here the renowned editor Evgeny Katz has chosen contributions that cover a wide range of examples and issues in implantable bioelectronics, resulting in an excellent overview of the topic. The various implants covered include biosensoric and prosthetic devices, as well...
Editeur :
Wiley-VCH
Parution :
2014-02-18
PDF, ePub
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Would it be cool to see woolly mammoth alive one day? Disappeared species have always fascinated the human mind. A new discussion of using genomic technologies to reverse extinction and to help in conservation has been sparked. This volume studies the question...
Editeur :
Palgrave Macmillan
Parution :
2014-02-07
PDF
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Proteolysis is an irreversible posttranslational modification affecting each and every protein from its biosynthesis to its degradation. Limited proteolysis regulates targeting and activity throughout the lifetime of proteins. Balancing proteolysis is therefore crucial...
Editeur :
Springer
Parution :
2014-01-21
ePub
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Deimination is a relatively new post-translational modification of proteins, whose recognition is ever-increasing. First linked to the pathology of rheumatoid arthritis (RA), deimination is a process by which selected positively charged arginine amino acids are...
Editeur :
Springer
Parution :
2013-12-03
ePub
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In this thesis, the author outlines the development of new monolithic columns and isotope dimethyl labeling strategies and their applications in high-performance proteome analyses. Though different types of monolithic columns have been widely developed for...
Editeur :
Springer
Parution :
2013-12-02
Collection :
Springer Theses
ePub
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Progressively builds a deep understanding of macromolecular behavior Based on each of the authors' roughly forty years of biophysics research and teaching experience, this text instills readers with a deep understanding of the biophysics of macromolecules. It sets a...
Editeur :
Wiley
Parution :
2013-11-25
PDF, ePub
Offre spéciale
-10%
151,95€
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Demonstrates how advances in plant chemical biology can translate to field applications With contributions from a team of leading researchers and pioneers in the field, this book explains how chemical biology is used as a tool to enhance our understanding of plant...
Editeur :
Wiley
Parution :
2013-11-05
PDF, ePub
Offre spéciale
-10%
129,95€
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The study of carbonic anhydrase has spanned multiple generations of scientists. Carbonic anhydrase was first discovered in 1932 by Meldrum and Roughton. Inhibition by sulfanilamide was shown in 1940 by Mann and Keilin. Even Hans Krebs contributed to early studies with a...
Editeur :
Springer
Parution :
2013-10-22
ePub
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Emerging evidence indicates that the Gadd45 family of genes play a unique and critical role as sensors of stress, including genotoxic, physiological and oncogenic stress. The stress response Gadd45 family of genes (Gadd45a, Gadd45b & Gadd45g), discovered by Dr....
Editeur :
Springer
Parution :
2013-10-08
ePub
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?Long non-coding RNAs (lnc)RNAs have emerged as a new paradigm in epigenetic regulation of the genome. Thousands of lncRNAs have been identified and observed in a wide range of organisms. Unlike mRNA, lncRNA have no protein-coding capacity. ?So, while their function is...
Editeur :
Springer
Parution :
2013-09-20
ePub
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This book describes the role of heat shock proteins in the life cycle of malaria parasites. The work includes a general introduction on the structural and functional features of heat shock proteins. The main focus is on the role of heat shock protein families from...
Editeur :
Springer
Parution :
2013-09-20
ePub
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A key experiment in biomedical research is monitoring the expression of different proteins in order to detect changes that occur in biological systems under different experimental conditions. The method that is most widely used is the Western blot analysis. While...
Editeur :
Springer
Parution :
2013-09-17
Collection :
SpringerBriefs in Systems Biology
ePub
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Although phosphorylation of proteins on tyrosine is relatively rare compared to phosphorylation on serine or threonine residues, the past two decades of research into PTP function have led to a great appreciation of the critical role PTPs have in regulating basic...
Editeur :
Springer
Parution :
2013-08-30
ePub
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Due to various special physiological features and a genome that greatly differs in structure, gene content and organization from other yeasts, Y. lipolytica is widely used as a host system. With its characteristics, such as the ability to grow on lipids or grease, to...
Editeur :
Springer
Parution :
2013-08-19
Collection :
Microbiology Monographs
ePub
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Due to various special physiological features and a genome that greatly differs in structure, gene content and organization from other yeasts, Y. lipolytica is widely used as a model organism. With its characteristics, such as the ability to accumulate oil and the high...
Editeur :
Springer
Parution :
2013-07-20
Collection :
Microbiology Monographs
ePub
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