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The knowledge of Th17 cells and other cell populations which secrete IL-17A, and/or IL-22 has expanded tremendously since the publication of the first edition “Th17 Cells: Role in Inflammation and Autoimmune Disease” in 2008.The present volume has been completely...
Editeur :
Springer
Parution :
2012-12-13
ePub
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GW bodies are novel cytoplasmic foci that were discovered and named by Dr. Chan’s group in 2002. These bodies are now known to be active cytoplasmic foci involved with the new gene regulation process mediated by microRNA that leads to translational repression and mRNA...
Editeur :
Springer
Parution :
2012-12-09
ePub
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In recent years, a number of groundbreaking structural and mechanistic studies deepened our understanding of helicase mechanisms and established new approaches for their analyses. Many fundamental mechanistic questions ranging from the mechanism of force generation,...
Editeur :
Springer
Parution :
2012-11-19
Collection :
Advances in Experimental Medicine and Biology
PDF, ePub
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A key goal in the treatment of cancer is to achieve selective and efficient killing of tumor cells. The aim of Cell Death Signaling in Cancer Biology and Treatment is to describe state-of-the-art approaches and future opportunities for achieving this goal by targeting...
Editeur :
Humana
Parution :
2012-11-19
ePub
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Life is an enduring mystery. Yet, science tells us that living beings are merely sophisticated structures of lifeless molecules. If this view is correct, where do the seemingly purposeful motions of cells and organisms originate? In Life's Ratchet, physicist Peter M....
Editeur :
Basic Books
Parution :
2012-10-30
ePub
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This book offers an in-depth analysis of the cell biology of cyanobacteria, a group of phototrophic microorganisms performing an important function in the biosphere. The chapters present the author’s and her colleagues’ pioneering investigations of the ultrastructure of...
Editeur :
Springer
Parution :
2012-10-28
ePub
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Prokaryotic Toxins – Antitoxins gives the first overview of an exciting and rapidly expanding research field. Toxin – antitoxin (TA) genes were discovered on plasmids 30 years ago. Since then it has become evident that TA genes are highly abundant in bacterial and...
Editeur :
Springer
Parution :
2012-10-19
ePub
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Protein kinases play a critical role in cellular processes that impact overall organismal health and function. Of the kinases that collectively make up the Human Kinome, CK2 has garnered special attention because of its significant role in the generation of the human...
Editeur :
Wiley-Blackwell
Parution :
2012-10-16
Collection :
The Wiley-IUBMB Series on Biochemistry and Molecular Biology
PDF, ePub
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At the forefront of life sciences today is the emerging discipline of chembiomolecular science. This new term describes the integration of the frontier fields of chemical biology, chemistry, and pharmacology. Chembiomolecular science aims to elucidate new biological...
Editeur :
Springer
Parution :
2012-10-02
ePub
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Endocytosis is a fundamental cellular process by means of which cells internalize extracellular and plasma membrane cargos for recycling or degradation. It is important for the establishment and maintenance of cell polarity, subcellular signaling and uptake of nutrients...
Editeur :
Springer
Parution :
2012-10-01
ePub
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Blood vessels of tumors display many structural and functional abnormalities. Their unusual leakiness, potential for rapid growth and remodeling, and expression of distinctive surface molecules mediate the dissemination of tumor cells in the bloodstream and maintain the...
Editeur :
Springer
Parution :
2012-09-28
ePub
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Computational methodologies and modeling play a growing role for investigating mechanisms, and for the diagnosis and therapy of human diseases. This progress gave rise to computational medicine, an interdisciplinary field at the interface of computer science and...
Editeur :
Springer
Parution :
2012-09-18
ePub
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Systems Biology of Apoptosis summarizes all current achievements in this emerging field. Apoptosis is a process common to all multicellular organisms. Apoptosis leads to the elimination of cells via a complex but highly defined cellular programme. Defects in the...
Editeur :
Springer
Parution :
2012-09-13
ePub
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In multicellular organisms, communication between cells involves secretion of proteins that bind to receptors on neighboring cells. While this has been well documented, another mode of intercellular communication has recently become the subject of increasing interest:...
Editeur :
Springer
Parution :
2012-09-06
ePub
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Biological O2 sensing probes and measurement techniques were first introduced in the late 80s. In the last 3-5 years they have undergone major development that have made them available and affordable for a broad range of applications in various disciplines of the life...
Editeur :
Springer
Parution :
2012-08-31
ePub
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This volume documents this unique family of cell surface proteins. Despite masquerading as intractable and difficult to clone and characterize, ENOX proteins have and continue to offer remarkable opportunities for research, commercial development and outside...
Editeur :
Springer
Parution :
2012-08-30
ePub
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Physics, mathematics and chemistry all play a vital role in understanding the true nature and functioning of biological membranes, key elements of living processes. Besides simple spectroscopic observations and electrical measurements of membranes we address in this...
Editeur :
Springer
Parution :
2012-08-28
ePub
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This book provides a detailed account of the physico-chemical properties and biological functions of the outer membrane vesicles (OMVs) of different pathogenic and non-pathogenic Gram-negative bacteria. It also includes an authentic record of the first systematic study...
Editeur :
Springer
Parution :
2012-08-01
ePub
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This volume covers data describing the role of free radicals and antioxidants that deal with clinical and pre-clinical trials, as well as basic research in the area of women's health. There is increasing evidence that oxidative stress is a causative, or at least a...
Editeur :
Humana
Parution :
2012-08-01
ePub
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Since the epochal discovery of the radical and highly toxic gas nitric oxide (NO) as a signaling molecule, two other no less toxic gases – carbon monoxide (CO) and hydrogen sulfide (H2S) – have been found to also be involved in a plethora of physiological and...
Editeur :
Springer
Parution :
2012-07-20
ePub
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