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The second volume in a new series dedicated to protein degradation, this book discusses the mechanism and cellular functions of targeted protein breakdown via the ubiquitin pathway. Drawing on the combined knowledge of the world's leading protein degradation experts,...
Editeur :
Wiley-VCH
Parution :
2008-06-25
Collection :
Protein Degradation
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Meeting the need for a book on developing and using new methods to investigate membrane proteins, this is the first of its kind to present the full range of novel techniques in one resource. Top researchers from around the world focus on the physical principles...
Editeur :
Wiley-Blackwell
Parution :
2008-06-25
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This final volume in the series focuses on malfunctions of the ubiquitin-proteasome system and their role in human disease. The editors and authors represent unmatched expertise, comprising virtually all the top scientists in the field, including the pioneers of...
Editeur :
Wiley-VCH
Parution :
2008-06-25
Collection :
Protein Degradation
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Editeur :
Springer
Parution :
2008-05-07
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'Homology' as a concept became increasingly elusive during the course of the 20th century. The central debates and controversies concern both fundamental definitions and the nature of the criteria by which homology is judged. Attempts to move away from comparative...
Editeur :
Wiley
Parution :
2008-04-30
Collection :
Novartis Foundation Symposia
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Gap Junction-Mediated Intercellular Signalling in Health and Disease Chairman: Norton B. Gilula 1999 The last few years have seen considerable progress in this field, and exciting new implications concerning the roles of gap junctional intercellular communication are...
Editeur :
Wiley
Parution :
2008-04-30
Collection :
Novartis Foundation Symposia
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Comprised of the latest developments in cell cycle research, it analyzes the principles underlying the control of cell division. Offers a framework for future investigation, especially that aimed toward understanding and treatment of cancer.
Editeur :
Wiley
Parution :
2008-04-30
Collection :
Novartis Foundation Symposia
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An international group of leading investigators discuss recent progress of sensory structures in lower and higher vertebrates. Experts in two relevant fields--the cell cycle and mitogenic growth factors--present insightful contributions in the search for precursors...
Editeur :
Wiley
Parution :
2008-04-30
Collection :
Novartis Foundation Symposia
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Experts from a variety of areas compare and discuss IL-6 and LIF in order to provide a new understanding of their modes of action, the significance of their polyfunctionalization--why the body chooses to use one molecule to regulate various cell types--and their...
Editeur :
Wiley
Parution :
2008-04-30
Collection :
Novartis Foundation Symposia
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Contributors to this volume explore the role of carbohydrates in communication between cells of multicellular organisms. Topics covered include the thermodynamics and spatial restrictions of oligosaccharide-protein interactions, the role of carbohydrates in recognition...
Editeur :
Wiley
Parution :
2008-04-30
Collection :
Novartis Foundation Symposia
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TGF-beta, originally identified as a transforming growth factor with similar properties, is now known to exist as a family of factors with similar properties. These factors promote cell proliferation in some tissue types or conditions and induce cell differentiation in...
Editeur :
Wiley
Parution :
2008-04-30
Collection :
Novartis Foundation Symposia
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Myopia, the most common disorder of the eye, affects 80% of the population of some countries. Although its basis remains uncertain, recent development of animal models have permitted tests of hypothesis as to myopia's origins. The symposium proceedings cover normal...
Editeur :
Wiley
Parution :
2008-04-30
Collection :
Novartis Foundation Symposia
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Presents state-of-the-art applications in hyaluronan research, from hyaluronan's physicochemical properties to its clinical role as a connective tissue marker and its surgical implications, particularly in ear, eye and orthopaedic surgery. Covers hyaluronan's synthesis...
Editeur :
Wiley
Parution :
2008-04-30
Collection :
Novartis Foundation Symposia
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An international group of researchers addresses basic mechanism involved in the metastatic spread of tumors and considers new methods of prevention and treatment. Compares behavior of normal and abnormal cells, with emphasis on cell surface mechanisms--especially...
Editeur :
Wiley
Parution :
2008-04-30
Collection :
Novartis Foundation Symposia
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Integrating classical knowledge of chromosome organisation with recent molecular and functional findings, this book presents an up-to-date view of chromosome organisation and function for advanced undergraduate students studying genetics. The organisation and behaviour...
Editeur :
Wiley-Blackwell
Parution :
2008-04-30
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The heat shock, or cell stress, response was first identified in the polytene chromosomes of Drosophila. This was later related to the appearance of novel proteins within stressed cells, and the key signal stimulating this appearance was identified as the presence of...
Editeur :
Wiley
Parution :
2008-04-30
Collection :
Novartis Foundation Symposia
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Controlled expansion of cell populations is a fundamental feature of living organisms, being a finely-tuned balance between cell proliferation and cell death. This book aims to explain the molecular mechanisms that lie behind the multiplication and survival of...
Editeur :
Wiley-Blackwell
Parution :
2008-04-15
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Written in an informal and accessible style, Chromatin and Gene Regulation enables the reader to understand the science of this rapidly moving field. Chromatin is a fundamental component in the network of controls that regulates gene expression. Many human diseases have...
Editeur :
Wiley-Blackwell
Parution :
2008-04-15
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Human Molecular Biology Laboratory Manual offers a hands-on, state-of-the-art introduction to modern molecular biology techniques as applied to human genome analysis. In eight unique experiments, simple step-by-step instructions guide students through the basic...
Editeur :
Wiley-Blackwell
Parution :
2008-04-15
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Detection and responses to light are common features found throughout the plant and animal kingdoms. In most primitive life forms, a patch of light-sensitive cells make up a region containing a cell sheet devoid of any specialized anatomical structure. With the...
Editeur :
Humana
Parution :
2008-04-09
Collection :
Ophthalmology Research
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