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This book comprehensively reviews the state-of-the-art strategies developed for protein-protein interaction (PPI) inhibitors, and highlights the success stories in new drug discovery and development. Consisting of two parts with twelve chapters, it demonstrates the...
Editeur :
Springer
Parution :
2018-06-26
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This book describes medical applications of photochemistry. In the first part, a general introduction to photochemistry and related phototechnologies is provided. In the second part, photochemistry-based medical applications for diagnostics (biochips and bioimaging) and...
Editeur :
Springer
Parution :
2018-06-21
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This book is the first to be entirely devoted to the challenging art of handling membrane proteins out of their natural environment, a key process in biological and pharmaceutical research, but one plagued with difficulties and pitfalls. Written by one of the foremost...
Editeur :
Springer
Parution :
2018-06-08
Collection :
Biological and Medical Physics, Biomedical Engineering
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This book addresses chemical and biological aspects related to sesquiterpene lactones (STLs). Experts in different fields have been invited to contribute on this class of compound's chemistry, isolation and identification, biological activities (antibacterial,...
Editeur :
Springer
Parution :
2018-06-07
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This book gathers selected peer-reviewed papers presented at the Second International Conference on Infectious Diseases and Nanomedicine (ICIDN), held in Kathmandu, Nepal on December 15–18, 2015. It also includes invited papers from the leading experts in the related...
Editeur :
Springer
Parution :
2018-05-21
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This book reviews the current strategies and challenges for the treatment of bacterial, fungal, parasitic and viral infectious diseases in developing countries. Contributing authors present expert analysis on the transmission, epidemiology, bacteriology, pathogenesis...
Editeur :
Springer
Parution :
2018-04-23
Collection :
Topics in Medicinal Chemistry
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This thesis discusses the use of asymmetric organic catalysis for the direct enantioselective synthesis of complex chiral molecules, and by addressing the many aspects of both vinylogy and atropisomerism, it appeals to researchers and scholars interested in both...
Editeur :
Springer
Parution :
2018-04-11
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This book investigates the use of palladium modified by bulky ligands as catalysts for new chemical transformations that rapidly assemble several classes of complex heterocyles. It documents the development of new chemical reactions involving carbon–carbon (C?C) and...
Editeur :
Springer
Parution :
2018-04-02
Collection :
Springer Theses
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This thesis presents the development of theranostic gold nanostars (GNS) for multimodality cancer imaging and therapy. Furthermore, it demonstrates that a novel two-pronged treatment, combining immune-checkpoint inhibition and GNS-mediated photothermal nanotherapy, can...
Editeur :
Springer
Parution :
2018-03-15
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This book explains theoretical and technological aspects of amorphous drug formulations. It is intended for all those wishing to increase their knowledge in the field of amorphous pharmaceuticals. Conversion of crystalline material into the amorphous state, as described...
Editeur :
Springer
Parution :
2018-02-09
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This brief describes studies conducted by the authors on mid-size drugs utilizing peptides and peptidomimetics, and on the development of anti-HIV agents. Peptides are important biological molecules and have various physiological actions. Peptide-based drug discovery...
Editeur :
Springer
Parution :
2018-01-16
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This book reviews skin permeation and disposition of chemical compounds. Skin is utilized as an administration site for transdermal drug delivery systems, topical drug formulations, cosmeceuticals, and cosmetics. Their usefulness is closely related to the permeation and...
Editeur :
Springer
Parution :
2017-11-28
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This unique book covers the latest developments in coupling and decoupling of biomolecules containing functionalized carbohydrate components, being one of the first collections in this important area of applied medicinal chemistry.Connecting molecules, often referred as...
Editeur :
Springer
Parution :
2017-11-20
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This thesis mainly describes the development of a screening process for a mirror-image library of chiral natural products. It demonstrates how, by using mirror-image proteins for the screening of available natural products, unavailable mirror-image isomers of natural...
Editeur :
Springer
Parution :
2017-11-03
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This Brief is devoted to the CFTR protein and cystic fibrosis, and it provides an updated perspective of the genetic, functional and cellular processes involved in this conformational disorder. Starting with a historical perspective on cystic fibrosis and its clinical...
Editeur :
Springer
Parution :
2017-10-01
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Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and...
Editeur :
Springer
Parution :
2017-09-26
Collection :
Topics in Medicinal Chemistry
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This book describes applications of acridines for the treatment of various neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, and various prion diseases, and discusses the potential of acridines in neuro-regenerative medicine. Using modern...
Editeur :
Springer
Parution :
2017-08-15
Collection :
Progress in Drug Research
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The first contribution presents coumarins, the largest group of 1-benzopyran derivatives found in plants. Coumarin chemistry remains one of the major interest areas of phytochemists, especially because of their structural diversity and medicinal properties, along with...
Editeur :
Springer
Parution :
2017-07-30
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The book covers theoretical background and methodology as well as all current applications of Quantitative Structure-Activity Relationships (QSAR). Written by an international group of recognized researchers, this edited volume discusses applications of QSAR in multiple...
Editeur :
Springer
Parution :
2017-05-22
Collection :
Challenges and Advances in Computational Chemistry and Physics
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Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and...
Editeur :
Springer
Parution :
2017-05-15
PDF, ePub
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