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DNA methyltransferases are important enzymes in a broad range of organisms. Dysfunction ofDNA methyltransferases in humans leads to many severe diseases, including cancer. This book focuses on the biochemical properties of these enzymes, describing their structures and...
Editeur :
Springer
Parution :
2016-11-08
PDF, ePub
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This book elucidates the genetic, biological, morphological and functional aspects of telocytes. Telocytes are a recently defined type of interstitial (stromal) cells, with very long (tens to hundreds of micrometres) and very thin prolongations (mostly below...
Editeur :
Springer
Parution :
2016-10-31
Collection :
Advances in Experimental Medicine and Biology
PDF, ePub
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This book gives an in-depth overview on nuclear structure and function. It clearly shows that the epigenome and the three-dimensional organization of the nucleus are not independent properties. The intimate relationship between the location and the epigenetic...
Editeur :
Springer
Parution :
2016-10-17
PDF, ePub
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This essential
volume comprehensively discusses redox-active therapeutics, focusing
particularly on their molecular design, mechanistic, pharmacological and
medicinal aspects. The first section of the book describes the basic
aspects of the chemistry and biology...
Editeur :
Springer
Parution :
2016-10-13
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This book explores the major cytokines, such as IL-1 and IFN-?, with respect to the regulation of their gene expression and protein production in specific immune cell types. It discusses both healthy physiological settings and in pathological situations in which the...
Editeur :
Springer
Parution :
2016-10-12
Collection :
Advances in Experimental Medicine and Biology
PDF, ePub
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This book discusses the immunotherapeutic potential of Interleukin 12 in the context of clinical oncology, as well as antitumor effects confirmed in preclinical studies and clinical trials in cancer immunotherapy. Due to its ability to activate both innate (NK cells)...
Editeur :
Springer
Parution :
2016-09-23
PDF, ePub
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This book provides an up-to-date overview of redox signaling in plant cells and its key role in responses to different stresses. The chapters, which are original works or reviews, focus on redox signaling states; cellular tolerance under different biotic and abiotic...
Editeur :
Springer
Parution :
2016-09-19
PDF, ePub
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Pancreatic islets make up the endocrine pancreas and they contain the only source of insulin in the body, beta cells. Hence, access to high quality preparations of pancreatic islets is fundamental for in vitro studies and to test pre-clinical applications in animal...
Editeur :
Springer
Parution :
2016-09-01
Collection :
Advances in Experimental Medicine and Biology
PDF, ePub
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This book describes the three gasotransmitters nitric oxide (NO), hydrogen sulphide (H2S) and carbon monoxide (CO) and their function as intracellular signalling molecules in plants. Common properties are shared by NO, H2S and CO: they are beneficial at low...
Editeur :
Springer
Parution :
2016-09-01
Collection :
Signaling and Communication in Plants
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This is the first book to provide a broad framework for obtaining an in depth understanding of the state-of-the-art knowledge on abnormalities of non-coding RNAs found to be associated with colorectal cancer pathogenesis. Readers will discover possible mechanisms...
Editeur :
Springer
Parution :
2016-08-29
PDF, ePub
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This textbook presents concise chapters written by internationally respected experts on various important aspects of cancer-associated metabolism, offering a comprehensive overview of the central features of this exciting research field. The discovery that tumor cells...
Editeur :
Springer
Parution :
2016-08-24
PDF, ePub
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Cancer, which has become the second-most prevalent health issue globally, is essentially a malfunction of cell signaling. Understanding how the intricate signaling networks of cells and tissues allow cancer to thrive - and how they can be turned into potent weapons...
Editeur :
Wiley-VCH
Parution :
2016-08-12
PDF, ePub
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The “omics” era has given a new perspective to the findings on the origin and evolution of the process of translation. This book provides insight into the evolution of the translation process and machinery from a modern perspective. Written by leading experts in...
Editeur :
Springer
Parution :
2016-08-10
PDF, ePub
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This book will cover the cutting-edge developments in molecular and cellular mechanobiology to date. Readers will have a clear understanding of mechanobiology at the molecular and cellular levels, encompassing the mechanosensors, transducers, and transcription. An...
Editeur :
Springer
Parution :
2016-08-10
Collection :
Physiology in Health and Disease
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This book aims to bridge the gap in understanding how protein-tyrosine phosphatases (PTPs), which carry out the reverse reaction of tyrosine phosphorylation, feature in cancer cell biology. The expertly authored chapters will first review the general features...
Editeur :
Springer
Parution :
2016-08-05
PDF, ePub
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In the context of the continual increase in the global incidence of diabetes, this book focuses on particular aspects of the disease such as the socio-economic burden and the effects on individuals and their families. It addresses a wide range of topics regarding its...
Editeur :
Springer
Parution :
2016-07-25
PDF, ePub
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Cell assays include all methods of measurements on living cells. Confined for a long time to research laboratories, these emerging methods have, in recent years, found industrial applications that are increasingly varied and, from now on, regulatory. Based on the recent...
Editeur :
Wiley-ISTE
Parution :
2016-07-14
PDF, ePub
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Ion channels are the major class of membrane proteins responsible for rapid and regulated transport of ions across biological membranes and for the generation and propagation of electrical signals in the brain, heart, and skeletal and vascular tissues.Ion channels are...
Editeur :
Springer
Parution :
2016-07-06
PDF
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The book conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding...
Editeur :
Springer
Parution :
2016-07-04
ePub
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This book summarizes our
current understanding about the biology and patho-biology of cardiomyocytes and
depicts common techniques for the study of these cells. The
book is divided into two parts; the first part provides insight into role and
function of cardiomyocytes...
Editeur :
Springer
Parution :
2016-06-28
ePub
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