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If theoretical physicists can seriously entertain canonical “standard models” even for the big-bang generation of the entire universe, why cannot life scientists reach a consensus on how life has emerged and settled on this planet? Scientists are hindered by conceptual...
Editeur :
Springer
Parution :
2011-08-31
ePub
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The book highlights work from many different labs that taught us abnormal HDACs potentially contribute to the development or progression of many human diseases including immune dysfunctions, heart disease, cancer, memory impairment, aging, and metabolic disorders.
Editeur :
Springer
Parution :
2011-08-31
Collection :
Handbook of Experimental Pharmacology
ePub
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Adhesive Interactions in Normal and Transformed Cells describes the basic mechanisms of the ability of tissue cells to attach to each other and to the extracellular matrix. These adhesive interactions are pivotal regulators of main cellular functions, such as...
Editeur :
Humana
Parution :
2011-08-31
ePub
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“... Useful background information is displayed in blue boxes, and good use is made of numerous tables and diagrams... a useful book for the undergraduate medical or allied health professional...” –Oncology News, May/June 2010 This forward looking cancer biology book...
Editeur :
Wiley-Blackwell
Parution :
2011-08-26
PDF, ePub
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This book aims to cover the knowledge of protein folding accumulated from studies of disulfide-containing proteins, including methodologies, folding pathways, and folding mechanism of numerous extensively characterized disulfide proteins. Folding of Disulfide Proteins...
Editeur :
Springer
Parution :
2011-08-12
Collection :
Protein Reviews
ePub
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The research field of biobanks and tissue research is highly promising. Many projects around the globe are involved in the collection of human tissue and health data for research purposes. These initiatives are driven by the perspective of decisive breakthroughs in the...
Editeur :
Springer
Parution :
2011-07-30
PDF, ePub
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The inflammasome was first described in 2002 as a molecular complex activating proinflammatory caspases and therefore regulating the maturation and biological activities of cytokines such as IL-1? and IL-18. This finding was substantiated by the identification of...
Editeur :
Springer
Parution :
2011-07-02
ePub
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The microenvironment in which a tumor originates plays a critical role in its initiation and progression. Tumor Microenvironment reviews the importance of tumor microenvironment in cancer management. Particular emphasis is placed on discussing how the unique...
Editeur :
Wiley
Parution :
2011-06-24
PDF, ePub
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The discovery of adult neurogenesis caused a paradigm shift in the neurosciences. For more than 100 years, it was believed that adult neurons do not regenerate. Joseph Altman and Fernando Nottebohm found proof to the contrary and changed the course of history. Their...
Editeur :
Springer
Parution :
2011-06-15
ePub
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A much-needed primer on the use of laser flow cytometry for stem cell analysis Laser flow cytometry is a powerful tool for rapid analysis of cells for marker expression, cell cycle position, proliferation, and apoptosis. However, no resources specifically address the...
Editeur :
Wiley-Blackwell
Parution :
2011-06-09
PDF, ePub
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This book features a special subsection of Nanomedicine, an application of nanotechnology to achieve breakthroughs in healthcare. It exploits the improved and often novel physical, chemical and biological properties of materials only existent at the nanometer scale. As...
Editeur :
Springer
Parution :
2011-05-26
ePub
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Cellular domains play vital roles in a wide range of cellular functions. Defining cellular domains and understanding the molecular basis of their formation is essential to the study of cell functionality. This authoritative reference provides the most comprehensive...
Editeur :
Wiley-Blackwell
Parution :
2011-05-18
PDF, ePub
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Transcription factors are the molecules that the cell uses to interpret the genome: they possess sequence-specific DNA-binding activity, and either directly or indirectly influence the transcription of genes. In aggregate, transcription factors control gene expression...
Editeur :
Springer
Parution :
2011-05-10
ePub
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An overview of the different approaches to cancer risk assessment of environmental factors - including "-omics" technologies, discussing the strengths and weaknesses of the methods in different fields. The main focus is on the carcinogenic effects of ionizing and...
Editeur :
Wiley-Blackwell
Parution :
2011-04-27
PDF, ePub
Offre spéciale
-7%
107,40€
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Although cell fusion is an omnipresent process in life, to date considerably less is still known about the mechanisms and the molecules being involved in this biological phenomenon in higher organisms. In Cell Fusion in Health and Disease Vol 1 & Vol 2 leading...
Editeur :
Springer
Parution :
2011-04-20
ePub
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Initially believed to be inactive molecules, glycans are now considered essential for life, both under normal and pathological conditions. This volume of the series “Biology of Extracellular Matrix” reviews the most recent findings on the role of glycans in the...
Editeur :
Springer
Parution :
2011-04-19
Collection :
Biology of Extracellular Matrix
ePub
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There is a widespread consensus that use of antioxidants as a therapeutic approach may counteract free radical mediated pathologies. However, the role of antioxidants in normal physiology and redox signaling is still in its infancy. Since oxidative stress is related to...
Editeur :
Humana
Parution :
2011-04-13
ePub
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The chapters of this book report cutting-edge research on molecular events in adiposity and type 2 diabetes, thus opening the way for innovative drug-based therapeutic strategies. It addresses all those who wish to keep in touch with recent developments in the field.
Editeur :
Springer
Parution :
2011-04-11
Collection :
Handbook of Experimental Pharmacology
ePub
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Regulated turnover of extracellular matrix (ECM) is an important component of tissue homeostasis. In recent years, the enzymes that participate in, and control ECM turnover have been the focus of research that touches on development, tissue remodeling, inflammation and...
Editeur :
Springer
Parution :
2011-04-07
Collection :
Biology of Extracellular Matrix
ePub
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Although cell fusion is an omnipresent process in life, to date considerably less is still known about the mechanisms and the molecules being involved in this biological phenomenon in higher organisms. In Cell Fusion in Health and Disease Vol 1 & Vol 2 leading...
Editeur :
Springer
Parution :
2011-03-23
ePub
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