Télécharger le livre :  Quantitative Decisions in Drug Development
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This book focuses on important decision points and evidence needed for making decisions at these points during the development of a new drug. It takes a holistic approach towards drug development by incorporating explicitly knowledge learned from the earlier part of the...

Editeur : Springer
Parution : 2021-09-03
Collection : Springer Series in Pharmaceutical Statistics
PDF, ePub

68,56
Télécharger le livre :  Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials
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This book provides an extensive overview of the principles and methods of sample size calculation and recalculation in clinical trials. Appropriate calculation of the required sample size is crucial for the success of clinical trials. At the same time, a sample size...

Editeur : Springer
Parution : 2020-11-19
Collection : Springer Series in Pharmaceutical Statistics
PDF, ePub

94,94
Télécharger le livre :  Statistics in Clinical and Observational Vaccine Studies
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This book offers an overview of the statistical methods used in clinical and observational vaccine studies. Pursuing a practical rather than theoretical approach, it presents a range of real-world examples with SAS codes, making the application of the methods...

Editeur : Springer
Parution : 2020-03-14
Collection : Springer Series in Pharmaceutical Statistics
PDF, ePub

94,94
Télécharger le livre :  Statistical Remedies for Medical Researchers
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This book illustrates numerous statistical practices that are commonly used by medical researchers, but which have severe flaws that may not be obvious.  For each example, it provides one or more alternative statistical methods that avoid misleading or incorrect...

Editeur : Springer
Parution : 2020-03-12
Collection : Springer Series in Pharmaceutical Statistics
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84,39
Télécharger le livre :  Planning and Analyzing Clinical Trials with Composite Endpoints
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This book addresses the most important aspects of how to plan and evaluate clinical trials with a composite primary endpoint to guarantee a clinically meaningful and valid interpretation of the results. Composite endpoints are often used as primary efficacy variables...

Editeur : Springer
Parution : 2018-05-22
Collection : Springer Series in Pharmaceutical Statistics
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137,14
Télécharger le livre :  Quantitative Decisions in Drug Development
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This book offers a high-level treatise of evidence-based decisions in drug development. Because of the inseparable relationship between designs and decisions, a good portion of this book is devoted to the design of clinical trials. The book begins with an overview of...

Editeur : Springer
Parution : 2017-05-25
Collection : Springer Series in Pharmaceutical Statistics
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68,56
Télécharger le livre :  Group Sequential and Confirmatory Adaptive Designs in Clinical Trials
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This book provides an up-to-date review of the general principles of and techniques for confirmatory adaptive designs. Confirmatory adaptive designs are a generalization of group sequential designs. With these designs, interim analyses are performed in order to...

Editeur : Springer
Parution : 2016-07-04
Collection : Springer Series in Pharmaceutical Statistics
ePub

137,14